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Vilardell Glycerin Suppositories Adults 3 G 12 Suppositories

Brand: Vilardell

Vilardell Adult Glycerin Suppositories (3 G 12 Suppositories)

Glycerol

ACTION AND MECHANISM

- [LAXANT]. Glycerol is a polyol derivative that behaves as a laxative when administered rectally. Its effects are due to a double mechanism of action:

 

* Irritant effect on the rectal mucosa, without affecting the distal walls of the intestine. The local contraction of the rectal muscles causes the expulsion of feces in a short time.

 

* Osmotic effect. Glycerol has a great hygroscopic capacity, causing the passage of water towards the intestinal lumen. The increase in water, together with the lubricating properties of sorbitol, soften the stool and facilitate its elimination.

 

The effects take between 15-30 minutes and an hour to appear.

PHARMACOKINETICS

- Absorption: Glycerol is barely absorbed when administered rectally, being almost completely eliminated when defecation occurs. However, oral absorption is high. Maximum oral plasma concentrations are reached within 60-90 minutes.

 

- Distribution: The absorbed glycerol is widely distributed throughout the body, accumulating in muscle fat.

 

- Metabolism: It is extensively metabolized in the liver (around 80% of the amount absorbed).

 

- Elimination: Glycerol is eliminated mainly by hepatic metabolism. In urine, 20% of the absorbed content appears unchanged. The elimination half-life is 30-45 minutes.

INDICATIONS

- [CONSTIPATION]. Symptomatic local treatment of temporary and occasional constipation.

POSOLOGY

- Adults, rectally: 1 suppository / 24 h (this is the general rule, although they can be administered when necessary, or according to medical criteria) or 1 application (adult rectal solution) / 24 h.


- Children and adolescents under 18 years of age, rectally:
* Children and adolescents over 12 years: 1 suppository / 24 h or 1 application (children rectal solution) / 24 h.
It is recommended not to use for periods longer than 6-7 days, except medical criteria. If after this time the symptoms continue or worsen, it is advisable to consult a doctor and / or pharmacist.

 

 

RULES FOR CORRECT ADMINISTRATION

- Suppositories: It is recommended to previously harden the suppositories by putting them 30 seconds under the cold water tap or 10 seconds in a glass of water. The suppositories will be inserted deep into the anal opening.

Repress the evacuation for as long as possible so that the medicine exerts its action perfectly.

 

CONTRAINDICATIONS

- Hypersensitivity to any component of the drug.

- Situations that could be aggravated by the laxative effect, such as [BOWEL OBSTRUCTION], [INTESTINAL PERFORATION], [INFLAMMATORY BOWEL DISEASE] chronic, [APPENDICITIS] or [TOXIC MEGACOLON]. Logically, it should not be used in patients with [DIARRHEA].

 

PRECAUTIONS

- Symptoms of intestinal obstruction. Before initiating treatment with a laxative, a differential diagnosis of intestinal obstruction is advised in patients with symptoms such as [NAUSEA], [VOMITING] or [ABDOMINAL PAIN] of unknown origin, or [ABDOMINAL DISTENSION].

 

ADVICE TO THE PATIENT

- Before starting treatment for constipation, lifestyle habits should be changed. It is recommended an adequate daily intake of fluids and fiber, respond quickly to the stimulus of defecation and perform physical exercise.

- This medicine should not be used by patients with intestinal obstructions.

 

- Consult your doctor and / or pharmacist in case of worsening constipation, or if symptoms such as nausea or vomiting, abdominal swelling or fever appear.

 

SPECIAL WARNINGS

- Perform a differential diagnosis in patients suspected of intestinal obstruction.

 

INTERACTIONS

No drug interactions have been described.

PREGNANCY

Animal safety : no data available.

Safety in Humans : Adequate and well-controlled studies in humans have not been performed. This medicine is to be used according to medical judgment.

Effects on Fertility : No specific studies have been performed in humans.

 

LACTATION

Glycerol administered rectally is poorly absorbed, and it is unknown whether it is excreted with milk. There are no studies that determine the possible consequences in the infant, so although its use is accepted, extreme precautions should be taken.

KIDS

Its use is not recommended in children under 12 years of age.

SENIORS

No specific problems have been described in this age group, although the use of laxatives in elderly patients on a chronic basis can trigger phenomena of orthostatic hypotension, weakness and motor incoordination due to loss of fluid and electrolytes.

ADVERSE REACTIONS

Glycerol adverse reactions are generally mild and transient, and local in nature.

 

- Digestive. Occasionally irritation, stinging or [ANAL PRURIT] may appear.

OVERDOSE

Symptoms: Using this medicine for long periods of time and at high doses can lead to irritable bowel syndrome.

 

Treatment: Treatment will be symptomatic. The administration of the laxative should be discontinued.

 

Package Leaflet Glycerin Suppositories Vilardell Adults 3 G 12 Suppositories

Brand: Vilardell
Isin: IK0ZOFJMFPRE

$13.16

$13.28
1% off
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Vilardell Glycerin Suppositories Adults 3 G 12 Suppositories

Vilardell Glycerin Suppositories Adults 3 G 12 Suppositories

$13.16 $13.28 (1% off)

Vilardell Adult Glycerin Suppositories (3 G 12 Suppositories)

Glycerol

ACTION AND MECHANISM

- [LAXANT]. Glycerol is a polyol derivative that behaves as a laxative when administered rectally. Its effects are due to a double mechanism of action:

 

* Irritant effect on the rectal mucosa, without affecting the distal walls of the intestine. The local contraction of the rectal muscles causes the expulsion of feces in a short time.

 

* Osmotic effect. Glycerol has a great hygroscopic capacity, causing the passage of water towards the intestinal lumen. The increase in water, together with the lubricating properties of sorbitol, soften the stool and facilitate its elimination.

 

The effects take between 15-30 minutes and an hour to appear.

PHARMACOKINETICS

- Absorption: Glycerol is barely absorbed when administered rectally, being almost completely eliminated when defecation occurs. However, oral absorption is high. Maximum oral plasma concentrations are reached within 60-90 minutes.

 

- Distribution: The absorbed glycerol is widely distributed throughout the body, accumulating in muscle fat.

 

- Metabolism: It is extensively metabolized in the liver (around 80% of the amount absorbed).

 

- Elimination: Glycerol is eliminated mainly by hepatic metabolism. In urine, 20% of the absorbed content appears unchanged. The elimination half-life is 30-45 minutes.

INDICATIONS

- [CONSTIPATION]. Symptomatic local treatment of temporary and occasional constipation.

POSOLOGY

- Adults, rectally: 1 suppository / 24 h (this is the general rule, although they can be administered when necessary, or according to medical criteria) or 1 application (adult rectal solution) / 24 h.


- Children and adolescents under 18 years of age, rectally:
* Children and adolescents over 12 years: 1 suppository / 24 h or 1 application (children rectal solution) / 24 h.
It is recommended not to use for periods longer than 6-7 days, except medical criteria. If after this time the symptoms continue or worsen, it is advisable to consult a doctor and / or pharmacist.

 

 

RULES FOR CORRECT ADMINISTRATION

- Suppositories: It is recommended to previously harden the suppositories by putting them 30 seconds under the cold water tap or 10 seconds in a glass of water. The suppositories will be inserted deep into the anal opening.

Repress the evacuation for as long as possible so that the medicine exerts its action perfectly.

 

CONTRAINDICATIONS

- Hypersensitivity to any component of the drug.

- Situations that could be aggravated by the laxative effect, such as [BOWEL OBSTRUCTION], [INTESTINAL PERFORATION], [INFLAMMATORY BOWEL DISEASE] chronic, [APPENDICITIS] or [TOXIC MEGACOLON]. Logically, it should not be used in patients with [DIARRHEA].

 

PRECAUTIONS

- Symptoms of intestinal obstruction. Before initiating treatment with a laxative, a differential diagnosis of intestinal obstruction is advised in patients with symptoms such as [NAUSEA], [VOMITING] or [ABDOMINAL PAIN] of unknown origin, or [ABDOMINAL DISTENSION].

 

ADVICE TO THE PATIENT

- Before starting treatment for constipation, lifestyle habits should be changed. It is recommended an adequate daily intake of fluids and fiber, respond quickly to the stimulus of defecation and perform physical exercise.

- This medicine should not be used by patients with intestinal obstructions.

 

- Consult your doctor and / or pharmacist in case of worsening constipation, or if symptoms such as nausea or vomiting, abdominal swelling or fever appear.

 

SPECIAL WARNINGS

- Perform a differential diagnosis in patients suspected of intestinal obstruction.

 

INTERACTIONS

No drug interactions have been described.

PREGNANCY

Animal safety : no data available.

Safety in Humans : Adequate and well-controlled studies in humans have not been performed. This medicine is to be used according to medical judgment.

Effects on Fertility : No specific studies have been performed in humans.

 

LACTATION

Glycerol administered rectally is poorly absorbed, and it is unknown whether it is excreted with milk. There are no studies that determine the possible consequences in the infant, so although its use is accepted, extreme precautions should be taken.

KIDS

Its use is not recommended in children under 12 years of age.

SENIORS

No specific problems have been described in this age group, although the use of laxatives in elderly patients on a chronic basis can trigger phenomena of orthostatic hypotension, weakness and motor incoordination due to loss of fluid and electrolytes.

ADVERSE REACTIONS

Glycerol adverse reactions are generally mild and transient, and local in nature.

 

- Digestive. Occasionally irritation, stinging or [ANAL PRURIT] may appear.

OVERDOSE

Symptoms: Using this medicine for long periods of time and at high doses can lead to irritable bowel syndrome.

 

Treatment: Treatment will be symptomatic. The administration of the laxative should be discontinued.

 

Package Leaflet Glycerin Suppositories Vilardell Adults 3 G 12 Suppositories

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Return: 

You may return most items within 30 days of delivery for a full refund.

To be eligible for a return, your item must be unused and in the same condition that you received it. It must also be in the original packaging.

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You should expect to receive your refund within four weeks of giving your package to the return shipper, however, in many cases you will receive a refund more quickly. This time period includes the transit time for us to receive your return from the shipper (5 to 10 business days), the time it takes us to process your return once we receive it (3 to 5 business days), and the time it takes your bank to process our refund request (5 to 10 business days).

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We'll pay the return shipping costs if the return is a result of our error (you received an incorrect or defective item, etc.). In other cases, you will be responsible for paying for your own shipping costs for returning your item. Shipping costs are non-refundable. If you receive a refund, the cost of return shipping will be deducted from your refund.

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If you discover your order is flawed please contact us Mail: support@ibspot.com. With photos of the wrong product we will providing a return shipping label. Once it is tracking we will ship a replacement a product immediately. 

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The fastest way to ensure you get what you want is to return the item you have, and once the return  is accepted, make a separate purchase for the new item. 

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