AOR R-Lipoic Acid 150mg - 90 V-Caps + BONUS
AOR R-Lipoic Acid 150mg - 90 V-Caps + BONUS
AOR R-Lipoic Acid 150mg - 90 V-Caps + BONUS
If you're taking a conventional lipoic acid pill, then you need to know that the health-promoting, anti-aging benefits associated with this nutrient are only being delivered by half of your supplement. The other half is worse than useless: it actually antagonizes the effects of the good half of the supplement. To put it bluntly: the lipoic acid you're taking harbors both a hero ... and an "evil twin." Many molecules used by the body have a specific "handedness" (chirality). For example, alpha-tocopherol, or essential fatty acids. In some cases, synthetic versions of these molecules have a different "handedness" than the natural molecule. You're probably familiar with some examples of this phenomenon, such as natural d- vs. synthetic dl-alpha-tocopherolor natural cis- vs. unnatural trans-fatty acids. Some of these artificial molecules are merely less potent than the natural forms, such as in the case of dl-alpha-tocopherol. But others are actually harmful - for example, trans-fatty acids.
Unless they specify otherwise, "lipoic acid" supplements are a 50/50 mixture of the natural R (+) lipoic acid, and the synthetic S (-) lipoic acid. These mixtures are called "racemates." In some cases, S (-) lipoic acid - or the racemate - is simply less effective than R (+) lipoic acid. But in other cases, the S (-) form actually acts in opposition to the activity of R (+) lipoic acid.
Glucose Metabolism
Insulin resistance, in which the cells of the body stop responding properly to the hormone insulin, happens to some degree in almost all of us as we age. Insulin resistance causes higher levels of insulin, blood sugar, and free fatty acids, all of which are threats to your health.
"We're finding - and others are, too - that the R (+) form - the natural form - is much more powerful than the racemic mixture ... Hopefully ... companies are going to be producing on more of a clinical scale the R (+) form of lipoic acid, because we're finding very significant effects using this, as opposed to the racemic mixture." - Dr. Tory Hagen, in Mitochondrial Decay in Aging.
"We have presented in this study new information indicating that this enhancement of glucose metabolism is sterospecific, with the R (+) enantiomer being much more effective than the S (-) enantiomer." - Dr. Ryan Streeper and colleagues, in The American Journal of Physiology.
"Lipoic acid sold in a health food store is a synthetic mixture, a racemic mixture. And R(+) is the natural form and S (-) is an unnatural one ... And in our hands R(+) works and S (-) doesn't." - Dr. Bruce Ames, in Strategies for Engineered Negligible Senescence.
"R (+) LA [that is, R (+) lipoic acid], and not a racemic mixture of R (+) and S (-) LA, should be considered a choice for therapeutic applications." - Dr. Lester Packer and colleagues, in Free Radical Biology and Medicine.
"The S (-) enantiomer ... part of the racemate, which is present as about a 50% impurity, needs to be eliminated." - Dr. Guido Zimmer and colleagues, in Methods in Enzymology.
Unless they specify otherwise, "lipoic acid" supplements are a 50/50 mixture of the natural R (+) lipoic acid, and the synthetic S (-) lipoic acid. These mixtures are called "racemates." In some cases, S (-) lipoic acid - or the racemate - is simply less effective than R (+) lipoic acid. But in other cases, the S (-) form actually acts in opposition to the activity of R (+) lipoic acid.
Glucose Metabolism
Insulin resistance, in which the cells of the body stop responding properly to the hormone insulin, happens to some degree in almost all of us as we age. Insulin resistance causes higher levels of insulin, blood sugar, and free fatty acids, all of which are threats to your health.
- Lipoic acid has been used to support healthy blood sugar metabolism. Scientists have compared the effects of the two "lipoic acid" molecules seperately.
- R (+) lipoic acid has emerged as the active ingredient in the racemate. R (+) lipoic acid fights all of the major effects of insulin resistance. The S(-)-form does not help in some of these areas, and even makes things worse in others.
- R (+) lipoic acid is more easily absorbed and taken into the cells than S (-) lipoic acid.
- Both forms of lipoic acid can be made more powerful by "charging" them up into their DHLA form. R (+) -lipoic acid is "upgraded" much more rapidly than S(-)-lipoic acid.
- Many studies have found that R (+) lipoic acid provides much more effective protection than S (-) lipoic acid or the racemate. In some cases, the S (-) lipoic acid actually counteracts the effects of R (+) lipoic acid.
- R (+) lipoic acid supplements partially reverse the age-associated loss of spatial and temporal memory seen in old animals.
- An animal study using R (+) lipoic acid found that it was able to significantly reduce age-related buildup of iron in the brain. Other studies suggest that S (-) lipoic acid will not work as well.
- R (+) lipoic acid, in animal experiments and in test-tube studies, makes mitochondria more efficient, so that they produce more energy and create fewer free radicals. Age-associated damage to mitochondrial structure is significantly reduced. S (-) lipoic acid does not have these effects, and may antagonize the action of R (+) lipoic acid.
- These benefits have a real impact on the organism. Animals undergoing a simulated heart attack recover heart function more rapidly when infused with R (+) lipoic acid; S (-) lipoic acid has no such effect.
- Animals who receive R (+) lipoic acid supplements look better and are more active.
- Many of the benefits of R( +) lipoic acid closely mimic those of caloric restriction. R (+) lipoic acid's effects on mitochondrial function are the most striking and unique parallel.
- A study in a short-lived strain of mouse demonstrated that R (+) lipoic acid can dramatically increase its lifespan. Neither S (-) lipoic acid, nor the racemate, had any significant effect.
- The National Institutes on Aging are currently funding studies to see if R (+) lipoic acid can truly slow down the aging process.
- Common "lipoic acid" supplements are thus like a house at war with itself. The S (-) form should be removed from supplements in favor of pure R (+) lipoic acid.
Antioxidant Defenses
Lipoic acid is known as a powerful and versatile antioxidant.
Neurological Health
Lipoic acid is known for its ability to protect brain and nerve cells from free radicals and toxins. Excessive levels of "transition metals" such as iron, copper, and cadmium are believed to play an important role in many neurological disorders. Having too much free iron in a key part of the brain has been implicated as a cause of Parkinson's disease, for example.
Mitochondrial Function
The biggest source of free radicals in your body are your cellular "power plants," the mitochondria. They are both the origin, and the target, of most of the free radical damage in the body. As we age, our mitochondria become less and less efficient, generating less and less energy while creating more and more free radicals.
Fundamental Aging
Nearly all researchers into the biology of aging agree that the decay of mitochondrial function is a major engine of the aging process. Caloric restriction, with adequate nutrition, is the only proven way to slow down the fundamental aging process in mammals.
The Bottom Line
"We're finding - and others are, too - that the R (+) form - the natural form - is much more powerful than the racemic mixture ... Hopefully ... companies are going to be producing on more of a clinical scale the R (+) form of lipoic acid, because we're finding very significant effects using this, as opposed to the racemic mixture." - Dr. Tory Hagen, in Mitochondrial Decay in Aging.
"We have presented in this study new information indicating that this enhancement of glucose metabolism is sterospecific, with the R (+) enantiomer being much more effective than the S (-) enantiomer." - Dr. Ryan Streeper and colleagues, in The American Journal of Physiology.
"Lipoic acid sold in a health food store is a synthetic mixture, a racemic mixture. And R(+) is the natural form and S (-) is an unnatural one ... And in our hands R(+) works and S (-) doesn't." - Dr. Bruce Ames, in Strategies for Engineered Negligible Senescence.
"R (+) LA [that is, R (+) lipoic acid], and not a racemic mixture of R (+) and S (-) LA, should be considered a choice for therapeutic applications." - Dr. Lester Packer and colleagues, in Free Radical Biology and Medicine.
"The S (-) enantiomer ... part of the racemate, which is present as about a 50% impurity, needs to be eliminated." - Dr. Guido Zimmer and colleagues, in Methods in Enzymology.
| Brand: | AOR |
| Isin: | IG4LZAEKB7UC |
This product is not available in the selected country
In Stock
Backordered
Out of Stock
IBspot Buyer Protection
Shop confidently on IBspot, receive your item as described or your money back for eligible orders. Learn Program Terms
GUARANTEED SAFE CHECKOUT
-
FREE Shipping
We offer FREE SHIPPING to all domestic orders.
-
EXCELLENT SUPPORT
We provide 24/7 online customer support via email.
-
MONEY BACK GUARANTEE
30 days money back guarantee, no additional fee charged.
If you're taking a conventional lipoic acid pill, then you need to know that the health-promoting, anti-aging benefits associated with this nutrient are only being delivered by half of your supplement. The other half is worse than useless: it actually antagonizes the effects of the good half of the supplement. To put it bluntly: the lipoic acid you're taking harbors both a hero ... and an "evil twin." Many molecules used by the body have a specific "handedness" (chirality). For example, alpha-tocopherol, or essential fatty acids. In some cases, synthetic versions of these molecules have a different "handedness" than the natural molecule. You're probably familiar with some examples of this phenomenon, such as natural d- vs. synthetic dl-alpha-tocopherolor natural cis- vs. unnatural trans-fatty acids. Some of these artificial molecules are merely less potent than the natural forms, such as in the case of dl-alpha-tocopherol. But others are actually harmful - for example, trans-fatty acids.
Unless they specify otherwise, "lipoic acid" supplements are a 50/50 mixture of the natural R (+) lipoic acid, and the synthetic S (-) lipoic acid. These mixtures are called "racemates." In some cases, S (-) lipoic acid - or the racemate - is simply less effective than R (+) lipoic acid. But in other cases, the S (-) form actually acts in opposition to the activity of R (+) lipoic acid.
Glucose Metabolism
Insulin resistance, in which the cells of the body stop responding properly to the hormone insulin, happens to some degree in almost all of us as we age. Insulin resistance causes higher levels of insulin, blood sugar, and free fatty acids, all of which are threats to your health.
"We're finding - and others are, too - that the R (+) form - the natural form - is much more powerful than the racemic mixture ... Hopefully ... companies are going to be producing on more of a clinical scale the R (+) form of lipoic acid, because we're finding very significant effects using this, as opposed to the racemic mixture." - Dr. Tory Hagen, in Mitochondrial Decay in Aging.
"We have presented in this study new information indicating that this enhancement of glucose metabolism is sterospecific, with the R (+) enantiomer being much more effective than the S (-) enantiomer." - Dr. Ryan Streeper and colleagues, in The American Journal of Physiology.
"Lipoic acid sold in a health food store is a synthetic mixture, a racemic mixture. And R(+) is the natural form and S (-) is an unnatural one ... And in our hands R(+) works and S (-) doesn't." - Dr. Bruce Ames, in Strategies for Engineered Negligible Senescence.
"R (+) LA [that is, R (+) lipoic acid], and not a racemic mixture of R (+) and S (-) LA, should be considered a choice for therapeutic applications." - Dr. Lester Packer and colleagues, in Free Radical Biology and Medicine.
"The S (-) enantiomer ... part of the racemate, which is present as about a 50% impurity, needs to be eliminated." - Dr. Guido Zimmer and colleagues, in Methods in Enzymology.
Unless they specify otherwise, "lipoic acid" supplements are a 50/50 mixture of the natural R (+) lipoic acid, and the synthetic S (-) lipoic acid. These mixtures are called "racemates." In some cases, S (-) lipoic acid - or the racemate - is simply less effective than R (+) lipoic acid. But in other cases, the S (-) form actually acts in opposition to the activity of R (+) lipoic acid.
Glucose Metabolism
Insulin resistance, in which the cells of the body stop responding properly to the hormone insulin, happens to some degree in almost all of us as we age. Insulin resistance causes higher levels of insulin, blood sugar, and free fatty acids, all of which are threats to your health.
- Lipoic acid has been used to support healthy blood sugar metabolism. Scientists have compared the effects of the two "lipoic acid" molecules seperately.
- R (+) lipoic acid has emerged as the active ingredient in the racemate. R (+) lipoic acid fights all of the major effects of insulin resistance. The S(-)-form does not help in some of these areas, and even makes things worse in others.
- R (+) lipoic acid is more easily absorbed and taken into the cells than S (-) lipoic acid.
- Both forms of lipoic acid can be made more powerful by "charging" them up into their DHLA form. R (+) -lipoic acid is "upgraded" much more rapidly than S(-)-lipoic acid.
- Many studies have found that R (+) lipoic acid provides much more effective protection than S (-) lipoic acid or the racemate. In some cases, the S (-) lipoic acid actually counteracts the effects of R (+) lipoic acid.
- R (+) lipoic acid supplements partially reverse the age-associated loss of spatial and temporal memory seen in old animals.
- An animal study using R (+) lipoic acid found that it was able to significantly reduce age-related buildup of iron in the brain. Other studies suggest that S (-) lipoic acid will not work as well.
- R (+) lipoic acid, in animal experiments and in test-tube studies, makes mitochondria more efficient, so that they produce more energy and create fewer free radicals. Age-associated damage to mitochondrial structure is significantly reduced. S (-) lipoic acid does not have these effects, and may antagonize the action of R (+) lipoic acid.
- These benefits have a real impact on the organism. Animals undergoing a simulated heart attack recover heart function more rapidly when infused with R (+) lipoic acid; S (-) lipoic acid has no such effect.
- Animals who receive R (+) lipoic acid supplements look better and are more active.
- Many of the benefits of R( +) lipoic acid closely mimic those of caloric restriction. R (+) lipoic acid's effects on mitochondrial function are the most striking and unique parallel.
- A study in a short-lived strain of mouse demonstrated that R (+) lipoic acid can dramatically increase its lifespan. Neither S (-) lipoic acid, nor the racemate, had any significant effect.
- The National Institutes on Aging are currently funding studies to see if R (+) lipoic acid can truly slow down the aging process.
- Common "lipoic acid" supplements are thus like a house at war with itself. The S (-) form should be removed from supplements in favor of pure R (+) lipoic acid.
Antioxidant Defenses
Lipoic acid is known as a powerful and versatile antioxidant.
Neurological Health
Lipoic acid is known for its ability to protect brain and nerve cells from free radicals and toxins. Excessive levels of "transition metals" such as iron, copper, and cadmium are believed to play an important role in many neurological disorders. Having too much free iron in a key part of the brain has been implicated as a cause of Parkinson's disease, for example.
Mitochondrial Function
The biggest source of free radicals in your body are your cellular "power plants," the mitochondria. They are both the origin, and the target, of most of the free radical damage in the body. As we age, our mitochondria become less and less efficient, generating less and less energy while creating more and more free radicals.
Fundamental Aging
Nearly all researchers into the biology of aging agree that the decay of mitochondrial function is a major engine of the aging process. Caloric restriction, with adequate nutrition, is the only proven way to slow down the fundamental aging process in mammals.
The Bottom Line
"We're finding - and others are, too - that the R (+) form - the natural form - is much more powerful than the racemic mixture ... Hopefully ... companies are going to be producing on more of a clinical scale the R (+) form of lipoic acid, because we're finding very significant effects using this, as opposed to the racemic mixture." - Dr. Tory Hagen, in Mitochondrial Decay in Aging.
"We have presented in this study new information indicating that this enhancement of glucose metabolism is sterospecific, with the R (+) enantiomer being much more effective than the S (-) enantiomer." - Dr. Ryan Streeper and colleagues, in The American Journal of Physiology.
"Lipoic acid sold in a health food store is a synthetic mixture, a racemic mixture. And R(+) is the natural form and S (-) is an unnatural one ... And in our hands R(+) works and S (-) doesn't." - Dr. Bruce Ames, in Strategies for Engineered Negligible Senescence.
"R (+) LA [that is, R (+) lipoic acid], and not a racemic mixture of R (+) and S (-) LA, should be considered a choice for therapeutic applications." - Dr. Lester Packer and colleagues, in Free Radical Biology and Medicine.
"The S (-) enantiomer ... part of the racemate, which is present as about a 50% impurity, needs to be eliminated." - Dr. Guido Zimmer and colleagues, in Methods in Enzymology.
Ingredients
- 150mg
- R(α) lipoic acid (sodium salt)*
- 100mcg
- Biotin
*Contains 15 mg sodium per capsule
Non-medicinal Ingredients:
sodium stearyl fumarate, dicalcium phosphate. Capsule: hypromellose, gellan gum.
Non-medicinal Ingredients:
sodium stearyl fumarate, dicalcium phosphate. Capsule: hypromellose, gellan gum.
Format
Veggie Caps
90 Vcaps
Dosage
Take one capsule three times daily with/without food, or as directed by a qualified health care practitioner.
Important Information
Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, soy, dairy, eggs, fish, shellfish or any animal by product. Consult a health care practitioner prior to use if you are pregnant, breastfeeding or if you have diabetes. If you experience sweating, paleness, chills, headaches, dizziness and/or confusion, discontinue use and consult a health care practitioner as these may be symptoms of serious low blood sugar.
Manufacturer Info
AOR Canada is the innovative formulators of Canada’s best-selling antioxidant support, AOR Advanced B Complex and AOR Tri-B12. They are also known for their top bone health supplements, Ortho Adapt and Bone Basics. You can also SHOP AOR's Nattokinase, and trusted Curcumin Ultra, Curcumin Active and Curcumin95 inflammation support at National Nutrition.ca. AOR are leaders in natural health with innovative product development.
Shipping Summary:
- Packages are shipped from Monday to Friday.
- The usual time for processing an order is 1 to 3 business days, but may vary depending on the availability of products ordered. This period excludes delivery times, which depend on your geographic location.
- We provide tracking for every order. Tracking will be available once your product is shipped. Each individual product may be shipped from different fulfillment centers across the globe as our product research team spends the time to source quality yet affordable products.
Estimated delivery times:
- Standard Shipping: 3-7 business days
- Expedited Shipping: 2-5 business days
- International Shipping: 10 - 15 business days
Please note that these are estimates, not guarantees. Delivery time depends on a number of variables, and there may be delays such as bad weather affecting air transport, or a package being held for inspection by Customs. ibspot is not liable for any delays in international transportation or customs clearance.
Shipments can be delivered directly to most addresses, except post office boxes. However, in certain remote areas, there may be an additional delivery charge or you may need to pick up your package from the closest service location of ibspot's shipping partner.
Shipping Status:
As soon as your order ships, you'll receive a shipping confirmation email that includes your tracking number.
If you don't receive a shipping confirmation email right away, don't worry! We know the delivery date or date range provided at checkout and we'll be sure to deliver the items within that timeframe.
Order changes:
Please contact our customer support if the order needs to be canceled or modified.
Item not received:
If you've successfully placed an order and haven't received it yet while the tracking status shows it's delivered. you'd wish to contact the carrier to hunt out your Cover as once the item is Covered we have control over it (once it’s by the carrier), but if still persists kindly email us
Damaged Parcel
If your package has been delivered in a PO Box, please note that we are not responsible for any damage that may result (consequences of extreme temperatures, theft, etc.).
If you have any questions regarding shipping or want to know about the status of an order, please contact us or email to support@ibspot.com.
Please Read Our Return & Refund Policy Carefully:
Return:
You may return most items within 30 days of delivery for a full refund.
To be eligible for a return, your item must be unused and in the same condition that you received it. It must also be in the original packaging.
Several types of goods are exempt from being returned. Perishable goods such as food, flowers, newspapers or magazines cannot be returned. We also do not accept products that are intimate or sanitary goods, hazardous materials, or flammable liquids or gases.
Additional non-returnable items:
- Gift cards
- Downloadable software products
- Some health and personal care items
To complete your return, we require a tracking number, which shows the items which you already returned to us.
There are certain situations where only partial refunds are granted (if applicable)
- Book with obvious signs of use
- CD, DVD, VHS tape, software, video game, cassette tape, or vinyl record that has been opened
- Any item not in its original condition, is damaged or missing parts for reasons not due to our error
- Any item that is returned more than 30 days after delivery
Items returned to us as a result of our error will receive a full refund,some returns may be subject to a restocking fee of 7% of the total item price, please contact a customer care team member to see if your return is subject. Returns that arrived on time and were as described are subject to a restocking fee.
Items returned to us that were not the result of our error, including items returned to us due to an invalid or incomplete address, will be refunded the original item price less our standard restocking fees.
You should expect to receive your refund within four weeks of giving your package to the return shipper, however, in many cases you will receive a refund more quickly. This time period includes the transit time for us to receive your return from the shipper (5 to 10 business days), the time it takes us to process your return once we receive it (3 to 5 business days), and the time it takes your bank to process our refund request (5 to 10 business days).
If you need to return an item, please Contact Us with your order number and details about the product you would like to return. We will respond quickly with instructions for how to return items from your order.
Shipping Cost
We'll pay the return shipping costs if the return is a result of our error (you received an incorrect or defective item, etc.). In other cases, you will be responsible for paying for your own shipping costs for returning your item. Shipping costs are non-refundable. If you receive a refund, the cost of return shipping will be deducted from your refund.
Depending on where you live, the time it may take for your exchanged product to reach you, may vary.
If you are shipping an item over $75, you should consider using a trackable shipping service or purchasing shipping insurance. We don’t guarantee that we will receive your returned item.
Refund:
- Purchases may be returned within 30 days of the shipping date for a refund.
- Refund will be issued to your original form of payment.
- Refunds for orders purchased with IBSPOT Gift Cards and/or IBSPOT Notes will be issued as a IBSPOT Gift Card and mailed to the original billing address. Gift cards cannot be redeemed for cash unless required by law.
Refund Processing
• Returns to a IBSPOT store will be refunded to the original form of payment or gift card. • Mail-in returns with our prepaid return label will be refunded back to the original form of payment within 3-5 business days after we receive your return. Please allow 5-7 business days for your return to arrive at our Returns Center.
• Note: It may take a few days until your bank posts the refund to your account.
Claims:
Claims related to the product. Be sure to check the details of your purchase carefully before you make the payment, and check the contents of the package(s) promptly upon receipt. If you have a problem with the product, visit our Support Center to find out about return shipping arrangements.
WHICH CIRCUMSTANCES WE OFFER RETURND & REFUND:
WRONG PRODUCT:
If you discover your order is flawed please contact us Mail: support@ibspot.com. With photos of the wrong product we will providing a return shipping label. Once it is tracking we will ship a replacement a product immediately.
Damages and issues
Please inspect your order upon reception and contact us immediately if the item is defective, damaged or if you receive the wrong item, so that we can evaluate the issue and make it right.
Exceptions / non-returnable items
Certain types of items cannot be returned, like perishable goods (such as food, flowers, or plants), custom products (such as special orders or personalized items), and personal care goods (such as beauty products). We also do not accept returns for hazardous materials, flammable liquids, or gases. Please get in touch if you have questions or concerns about your specific item. Unfortunately, we cannot accept returns on sale items or gift cards.
Exchanges
The fastest way to ensure you get what you want is to return the item you have, and once the return is accepted, make a separate purchase for the new item.
Oops!
Sorry, it looks like some products are not available in selected quantity.
